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Overview
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TXNL4B produced in E. Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids (1-149 a.a) and having a molecular mass of 21.1kDa. TXNL4B is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TXNL4B is a member of the DIM1 family which has a vital role in pro-mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome.
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Overview