Name: Recombinant Human TBC1 Domain Family, Member 1
Price: Inquiry

- Overview
  - TBC1D1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 288 amino acids (1-265 a.a) and having a molecular mass of 33.2kDa. TBC1D1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TBC1D1belongs to a family of proteins sharing a 180-200 a.a TBC domain having a rolein regulating cell growth and differentiation of various tissues. Theseproteins share significant homology with TRE2, yeast Bub2, and CDC16. TBC1D1function as a GTPase-activating protein for Rab family proteins. TBC1D1 isinvolved in the trafficking and translocation of GLUT4-containing vesicles andinsulin-stimulated glucose uptake into cells. Among the diseases associatedwith TBC1D1 are tuberculous meningitis, and meningitis.
    
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- Properties
  - Protein Name
    
    TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1, KIAA1108, TBC, TBC1, TBC1 Domain Family Member 1.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    TBC1D1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human TBC1 Domain Family, Member 1

Recombinant Human TBC1 Domain Family, Member 1

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