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Overview
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STX12 Human Recombinant produced in E. coli is a single polypeptide chain containing 272 amino acids (1-248) and having a molecular mass of 31.0kDa. STX12 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. STX12 is a member of the syntaxin family which are cellular receptors for transport of vesicles that take part in exocytosis in neutrophils. STX12 regulates protein transport from late endosomes and the trans-Golgi network and back. Additionally, STX12 cooperates with ABC1 (ATP-binding cassette transporter A1), which enables cellular release of cholesterol and choline-phospholipids to apoA-I (apolipoprotein A-I).
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Overview