Recombinant Human SRY (sex determining region Y)-box 2 TAT

Recombinant Human SRY (sex determining region Y)-box 2 TAT

Catalog Number:
P001414148ABE
Mfr. No.:
Abe32-4927
Price:
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • Sox2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 330 amino acids (317 aa residues of the full length Sox2) and having a molecular mass of 36kDa. Sox2 is fused to a 13 amino acid TAT peptide at C-terminus (GGYGRKKRRQRRR) & purified by proprietary chromatographic techniques. SOX2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX4 is important for early embryogenesis and for embryonic stem cell pluripotency.

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      • Properties
        • Protein Name
          MCOPS3, ANOP3, MGC2413, SOX2, SRY (sex determining region Y)-box 2.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
          Formulation
          Lyophilized from a 0.2µm filtered concentrated solution in 2xPBS, pH 7.4 and 5% trehalose.
          Storage
          Lyophilized Sox2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Sox2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to reconstitute the lyophilized Sox2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

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