Recombinant Human Syndecan-4

Recombinant Human Syndecan-4

Catalog Number:
P001413841ABE
Mfr. No.:
Abe32-4783
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • SDC4 Human Recombinant produced in E. Coli is a single, non-glycosylated,polypeptide chain containing 128 amino acids (19-145a.a.) and having a molecular mass of 13.9 kDa. SDC4 is purified by proprietary chromatographic techniques. Syndecan-4 is a type I integral membrane heparan sulfate proteoglycan (HSPG), which was originally isolated from cloned rat microvascular endothelial cells as an antithrombin-binding molecule, and is now known to be a member of the syndecan family. Syndecan-4 binds to basic fibroblast growth factor (bFGF), midkine, and tissue factor pathway inhibitor via its heparan sulfate chains, and is thought to be involved in various biologic functions such as signaling of bFGF, anticoagulation, and focal adhesion formation. A previous study demonstrated that syndecan-4 is expressed in various tissues, and its level of expression in the kidney is stronger than those of other syndecan family members. Thus, syndecan-4 is thought to play certain roles in maintaining renal function. Moreover, it has been reported that proteoglycans, especially sulfated proteoglycans, are involved in organogenesis of the kidney.

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      • Properties
        • Protein Name
          SDC-4, SYND4, SYND-4, Amphiglycan, Ryudocan core protein, Syndecan-4.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85% as determined by SDS-PAGE.
          Formulation
          Syndecan-4 (1mg/ml) protein solution containing 20mM Tris-HCl pH-8, and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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