Name: Recombinant Mouse Receptor-Associated Protein Of The Synapse
Price: Inquiry

- Overview
  - RAPSN Mouse Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 435 amino acids (1-412aa) and having a molecular mass of 48.8kDa. RAPSN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.43kDa receptor-associated protein of the synapse (RAPSN), is expressed in the postsynapticmembrane of skeletal muscle. RAPSN is essential for the clustering of nicotinicacetylcholine receptors (nAChR). In addition RAPSN self-associates via at leasttwo of its seven tetra-tricopeptide repeats (TPRs). RAPSN interacts withthe large intracellular domain of the nAChR a subunit all the way through thehydrophobic surface of the coiled-coil domain. RAPSN modifies trafficking of AChR within the cell. Overexpressioninhibits agrin-induced AChR clustering pathway. RAPSN also plays a role inpostsynaptic congenital myasthenic syndromes.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Receptor-Associated Protein Of The Synapse, 43 KDaPostsynaptic Protein, Acetylcholine Receptor-Associated 43 KDa Protein, RNF205, RING Finger Protein 205, rapsyn, Receptor-Associated Protein Of The Synapse, 43Kd, 43 KDa Receptor-Associated Protein O
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 85% as determined by SDS-PAGE.
    
    Formulation
    
    RAPSN protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Mouse Receptor-Associated Protein Of The Synapse

Recombinant Mouse Receptor-Associated Protein Of The Synapse

We Also Recommend

Recombinant Human Retinoic Acid Receptor Responder 1

Recombinant Human Retinoic Acid Receptor Responder 2

Recombinant Retnoid Acid Receptor Alpha