Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide G

Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide G

Catalog Number:
P001414133ABE
Mfr. No.:
Abe32-4909
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • SNRPG Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 96 amino acids (1-76 a.a.) and having a molecular mass of 10.6kDa. The SNRPG is purified by proprietary chromatographic techniques. Small nuclear ribonucleoprotein polypeptide G (SNRPG) is a member of the snRNP Sm proteins family. There are at least 7 isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins has a vital role in the biogenesis of the snRNPs. The human Sm G genes are mapped to chromosomes 2. Furthermore, these proteins represent the major targets for the supposed anti-Sm auto-antibodies which are diagnostic for SLE (systemic lupus erythematosus). One class of these autoantibodies reacts specifically with native Sm E-F-G complexes.

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      • Properties
        • Protein Name
          Small nuclear ribonucleoprotein G, snRNP-G, Sm protein G, Sm-G, SmG, SNRPG, PBSCG, MGC117317.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95.0% as determined by SDS-PAGE.
          Formulation
          The SNRPG solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 50% glycerol and 0.1M NaCl.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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