Name: Recombinant Human Suppressor of Cytokine Signaling 3
Price: Inquiry

- Overview
  - SOCS3 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-225 a.a) and having a molecular mass of 29kDa. SOCS3 is fused to a 37 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Suppressorof Cytokine Signaling 3, also known as SOCS3 belongs to the SOCS family; inaddition SOCS3 is a member of the STAT-induced STAT inhibitor (SSI). The SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by different cytokines, including IL6, IL10, and interferon (IFN)-gamma. SOCS3 can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of SOCS3 have shown the roles of SOCS3 in the negative regulation of fetal liver hematopoiesis, and placental development.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Suppressor Of Cytokine Signaling 3, CIS3, SSI3, Cytokine-InducibleSH2 Protein 3, STAT-Induced STAT Inhibitor 3, ATOD4, Cish3, MGC71791, CIS-3.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 90% as determined by SDS-PAGE.
    
    Formulation
    
    SOCS3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Suppressor of Cytokine Signaling 3

Recombinant Human Suppressor of Cytokine Signaling 3

We Also Recommend

Recombinant Human Superoxide Dismutase His Tag

Recombinant Human Superoxide Dismutase-1

Recombinant Human Superoxide Dismutase-2