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Recombinant Human RIPK1 (N-GST tag)

Recombinant Human RIPK1 (N-GST tag)

Catalog Number:
E001278535APP
Mfr. No.:
Z500338
Price:
$1,110
  • Size:
    10 µg
    Quantity:
    Add to Cart:
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      • Overview

        • RIPK1 or Receptor Interacting Protein Kinase 1 is a serine/threonine kinase that was originally identified as interacting with the cytoplasmic domain of FAS. RIPK1 has been deemed as an important element in the signal transduction machinery that mediates programmed cell death. RIPK1 has been shown to interact with TRADD, TRAF1 TRAF2 and TRAF3 and TRADD can act as an adaptor protein to recruit RIPK1 to the TNFR1 complex in a TNF-dependent process. TNFalpha is capable of activating the noncanonical NF-kB pathway, but this activation of this pathway is negatively regulated by RIPK1.

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      • Properties
        • Name
          RCK; MAP3K19
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          108.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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