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Recombinant human PSCA protein with C-terminal human Fc

Recombinant human PSCA protein with C-terminal human Fc

Catalog Number:
P001418049ABE
Mfr. No.:
Abe32-17064
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      • Overview

        • The protein has a predicted molecular mass of 34.4 kDa after removal of the signal peptide. The apparent molecular mass of PSCA-hFc is approximately 40-57 kDa due to glycosylation. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

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      • Properties
        • Protein Name
          PSCA, UNQ206, PRO232
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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