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Recombinant human SELP protein with C-terminal human Fc tag

Recombinant human SELP protein with C-terminal human Fc tag

Catalog Number:
P001418051ABE
Mfr. No.:
Abe32-17066
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      • Overview

        • The protein has a predicted molecular mass of 106.1 kDa after removal of the signal peptide. The apparent molecular mass of SELP-hFc is approximately 130-150 kDa due to glycosylation. This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

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      • Properties
        • Protein Name
          P-Selectin, CD62P, SELP, GMP-140
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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