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Overview
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Procalcitonin (PCT) is a 116 amino acid residue protein with a molecular weight of approximately 13kDa. It is secreted by a variety of different cells from numerous organs in response to proinflammatory stimulation. PCT has been identified as an important marker to use for the diagnosis and management of bacterial infections and sepsis. PCT is also extremely useful for physicians as it enables specific differentiation between a bacterial infection and any other causes of inflammatory reactions, (such as viral infections, allergies, autoimmune disease and graft rejection) which do not lead to a significant increase in PCT.
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