Name: Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(N-His)
Price: Inquiry

- Overview
  - NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and is a member of the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins mainly expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. Studies showed that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type II integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 acts as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in the nomenclature of CD antigens. The increased expression of NKG2A in tumor infiltrating NK cells is emerging as a contributor in determining the poor prognosis of hepatocellular, lung or other carcinomas and in some cases may be a predictive factor of tumor metastasis.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    NKG2-A/NKG2-B type II integral membrane protein; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD159a; KLRC1; NKG2A
    
    Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 um filtered solution of PB, pH7.4
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(N-His)

Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(N-His)

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