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Overview
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NFKBID Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 336 amino acids (1-313) and having a molecular mass of 35.9 kDa. NFKBID is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. NFKBID belongs to the IkB family of proteins which contains four groups (IkB-alpha, IkB-beta, IkB-gamma, IkB-epsilon). NFKBID takes part in regulating inflammatory responses and cytokine, IL-2 and IL-6 expression through NFkB activity. NFKBID has 3 known alternative spliced isoforms, and is associated with RelB, NFB p50 and NFkB p65 in nucleus. NFKBID is involeved in thymocyte selection in response to TCR induction.
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Overview