Name: Recombinant Human Myeloid Cell Nuclear Differentiation Antigen
Price: Inquiry

- Overview
  - MNDA Human Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 427 amino acids (1-407 a.a.) and having a molecular mass of 47.9 kDa. The MNDA is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. MNDA plays a role as a transcriptional activator/repressor in the myeloid lineage and in the granulocyte/monocyte cell-specific response to interferon. MNDA Stimulates the DNA binding of the transcriptional repressor protein YY1. MNDA is identified only in nuclei of cells of the granulocyte-monocyte lineage. A 200-a.a region of human MNDA is remarkably related to a region in the proteins encoded by a family of interferon-inducible mouse genes, MNDA participates in blood cell-specific responses to interferons.
    
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- Properties
  - Protein Name
    
    PYHIN3, Myeloid cell nuclear differentiation antigen, MNDA.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    The MNDA solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.
    
    Storage
    
    MNDA although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Myeloid Cell Nuclear Differentiation Antigen

Recombinant Human Myeloid Cell Nuclear Differentiation Antigen

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