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Overview
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MOAP1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 374 amino acids (1-351a.a) and having a molecular mass of 41.9kDa. MOAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Modulatorof apoptosis 1 (MOAP1), is a member of the PNMA family and contains one BH3-like domainand one RASSF1-binding domain. MOAP1 was recognized by its interaction withapoptosis regulator BAX protein. MOAP1 includes a Bcl-2 homology 3 (BH3)-likemotif, which is essential for the association with BAX. In addition, once overexpressed MOAP1 mediates caspase-dependent apoptosis.
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Overview