-
-
Overview
-
MREG Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) andhaving a molecular mass of 27.3kDa. MREG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Melanoregulin(MREG) takes part in membrane fusion and in regulating the biogenesis of diskmembranes of photoreceptor rods. MREG is expressed in photoreceptor cells astwo isoforms as a result of alternative splicing. MREG interacts withPeripherin-2, a photoreceptor specific tetraspanin protein which is required topreserve normal cell structure during the renewal process of membrane fusion. Moreover, MREG plays a part in the incorporation of pigments into hair.
Please contact us at for specific academic pricing.
-
- Properties
-
Overview