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Overview
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MOCS2 Human Recombinant produced in E. coli is a single polypeptide chain containing 224 amino acids (1-188) and having a molecular mass of 25.0 kDa. MOCS2 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Molybdenum Cofactor Synthesis 2 (MOCS2) is a heterotetrameric synthase comprised of 2 small (MOCS2A) and 2 large (MOCS2B) subunits. Both the large and small subunits of molybdopterin synthase are encoded from the MOCS2 gene by overlapping open reading frames. MOCS2 operates in the second step of the molybdenum cofactor or molybdopterin (MPT) synthesis. MOCS2 catalyzes the formation of MPT from precursor Z by incorporating a dithiolene functional group.
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Overview