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Recombinant Human MEK5 (N-GST tag)

Recombinant Human MEK5 (N-GST tag)

Catalog Number:
E001278416APP
Mfr. No.:
Z500216
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • MEK5 or MAP2K5 (mitogen-activated protein kinase kinase 5) is a dual specificity protein kinase that belongs to the MAP kinase kinase family which specifically interacts with and activates MAPK7/ERK5. MEK5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MEK5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MEK5 promoter may affect the risk of developing colorectal cancer (CRC).

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      • Properties
        • Name
          MAP2K5, MAPKK5, MKK5, PRKMK5, SAPKK5; SKK5; HsT17454
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          77.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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