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Recombinant Human MEK1 (N-GST tag)

Recombinant Human MEK1 (N-GST tag)

Catalog Number:

E001278418APP

Mfr. No.:

Z500214

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - MEK1 is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. Constitutive activation of MEK1 results in cellular transformation. Thus, MEK1 represents a likely target for pharmacologic intervention in proliferative disease such as cancer.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    MAP2K1, MKK1, MAPKK1, PRKMK1
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    72.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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