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Overview
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Alphat-1 Antitrypsin (AAT) is a serine protease inhibitor. It protects tissues from enzymes of inflammatory cells, especially neutrophil elastase. If it is deficiency, neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children. OsrhAAT is derived from rice grain, which contains 384 amino acids with a molecular weight of 46.7 kD. The rice endosperm platform makes the manufacture capability at hundreds of gram scales to meet your bioprocessing needs.
Please contact us at for specific academic pricing.
Background
OryzHiExp - A Rice Endosperm Specific Expression Platform
OryzHiExp platform uses rice endosperm cells to express various recombinant proteins and small peptides at high levels. Through this platform, innovative animal-free protein products with a wide range of applications can be produced, such as OsrHSA, OsrhTF, OsrhFN, and other recombinant growth factors.
ADVANTAGES
• Elimination of the potential risk of viral and other unknown contaminants
• Avoid the quality changes from different batches, improve the repeatability of cellculture and experiment results
• Regulatory compliant with well-defined components
• Stable supply and manufacture capability at large scales to meet bulk processing needs
• Simplify the downstream bio-processing or biological research
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