Name: Recombinant Human Kruppel-Like Factor 12
Price: Inquiry

- Overview
  - KLF12 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 425 amino acids (1-402 a.a) and having a molecular mass of 46.6kDa. KLF12 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Krueppel-like factor 12 (KLF12) belongs to the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a particular site in the AP-2 alpha gene promoter. AP-2 alpha (Activator protein-2 alpha) is a developmentally-regulated transcription factor and vital regulator of gene expression during vertebrate development and carcinogenesis. KLF12 gene repression entails binding with a corepressor, CtBP1.
    
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- Properties
  - Protein Name
    
    AP-2rep, AP2REP, HSPC122, Krueppel-like factor 12, Transcriptionalrepressor AP-2rep.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    KLF12 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH8.0) , 10% glycerol and 0.4M Urea.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Kruppel-Like Factor 12

Recombinant Human Kruppel-Like Factor 12

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