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Recombinant human FAP Protein with N-terminal His Tag

Recombinant human FAP Protein with N-terminal His Tag

Catalog Number:
P001417552ABE
Mfr. No.:
Abe32-17131
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      • Overview

        • The protein has a predicted molecular mass of 85.9 kDa after removal of the signal peptide. The apparent molecular mass of His-FAP is approximately 95-130 kDa due to glycosylation. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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      • Properties
        • Protein Name
          FAP, FAPalpha, SIMP, Seprase, APCE
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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