Recombinant Human CB1 protein with C-terminal human Fc

Recombinant Human CB1 protein with C-terminal human Fc

Catalog Number:
P001417556ABE
Mfr. No.:
Abe32-17135
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      • Overview
        • The protein has a predicted molecular mass of 44.2 kDa after removal of the signal peptide. The apparent molecular mass of CB1-hFc is approximately 70-100 kDa due to glycosylation. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

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      • Properties
        • Protein Name
          CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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