Recombinant Human ERN1 (IRE1) (N-GST tag)

Recombinant Human ERN1 (IRE1) (N-GST tag)

Catalog Number:
E001278327APP
Mfr. No.:
Z500135
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • ERN1 or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals. ERN1 controls IRE1 proteolysis in mammalian cells. The activation of ERN1 through oligomerization expands the mechanistic repertoire of kinase-based signaling receptors. ERNI has a critical function in extraembryonic cells that is essential for fetal viability.

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      • Properties
        • Name
          hIRE1p; IRE1; IRE1A; IRE1P
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          87.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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