Name: Recombinant Human ERK5 (N-GST tag)
Price: 672.00 USD

- Overview
  - ERK5 is a member of the MAP kinase family and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. ERK5 is activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) and is involved in downstream signaling processes of various receptors. In response to extracelluar signals, ERK5 translocates to cell nucleus where it regulates gene expression by phosphorylating and activating different transcription factors. Gene deletion of ERK5 in mice results in defective blood vessel and cardiac development leading to embryonic lethality. ERK5 has been shown to be critical for endothelial function and maintenance of blood vessel integrity.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    MAPK7, BMK1, ERK4, PRKM7
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    132.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

Recombinant Human ERK5 (N-GST tag)

Recombinant Human ERK5 (N-GST tag)

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