Name: Recombinant Human ER a-1,2-Mannosidase/MAN1B1 (C-6His)
Price: Inquiry

- Overview
  - MW : 68.7kD. Recombinant Human MAN1B1 is produced by our Mammalian expression system and the target gene encoding Asp106-Ala699 is expressed with a 6His tag at the C-terminus. Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-a-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
    
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- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 50mM TrisHCL, 10mM reduced Glutathione, pH 8.0.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q9UKM7
    
    Gene ID
    
    11253
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human ER a-1,2-Mannosidase/MAN1B1 (C-6His)

Recombinant Human ER a-1,2-Mannosidase/MAN1B1 (C-6His)

More Information

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