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Recombinant human EGFR Protein with C-6×His tag

Recombinant human EGFR Protein with C-6×His tag

Catalog Number:
P001417534ABE
Mfr. No.:
Abe32-17118
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      • Overview

        • The protein has a predicted molecular mass of 69.4 kDa after removal of the signal peptide. The apparent molecular mass of EGFR-His is approximately 100-130 kDa due to glycosylation. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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      • Properties
        • Protein Name
          EGFR, ERBB, ERBB1, HER1, PIG61, mENA
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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