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Recombinant human TGFBR1 Protein with N-Human Fc tag

Recombinant human TGFBR1 Protein with N-Human Fc tag

Catalog Number:
P001417537ABE
Mfr. No.:
Abe32-17120
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      • Overview

        • The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide. The apparent molecular mass of hFc-TGFBR1 is approximately 40-53 kDa due to glycosylation. The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

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      • Properties
        • Protein Name
          AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TBR-i; TBRI; TGFR-1
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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