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Recombinant Human CK1 alpha 1 (N-GST tag)

Recombinant Human CK1 alpha 1 (N-GST tag)

Catalog Number:

E001278277APP

Mfr. No.:

Z500083

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - CK1a1 is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes. CK1a1 can regulate Smo cell surface accumulation and activity in response to hedgehog. CK1a1 phosphorylate Smo at several sites and phosphorylation-deficient forms of Smo fail to accumulate on the cell surface and are unable to transduce the hedgehog signal. CK1a1 dynamically associates with the CBM complex on T cell receptor engagement to participate in cytokine production and lymphocyte proliferation. CK1a1 can form complex with MDM2 which then regulates the stability of p53 and E2F-1 transcription factors.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    CSNK1A1, CK1, HLCDGP1, PRO2975, CK1A1
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    62.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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