Recombinant Human CDK1/CyclinB1 (N-GST tag)

Recombinant Human CDK1/CyclinB1 (N-GST tag)

Catalog Number:
E001278259APP
Mfr. No.:
Z500065
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.

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      • Properties
        • Name
          CDK1: CDC2 CyclinB1: CCNB1, CCNB
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          58.0kDa, 75.0kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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