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Recombinant Human CDK1/CyclinA2 (N-GST tag)

Recombinant Human CDK1/CyclinA2 (N-GST tag)

Catalog Number:

E001278257APP

Mfr. No.:

Z500064

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    CDK1: CDC2 CDC28A; MGC111195; DKFZp686L20222 CyclinA2: CCN1; CCNA
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    59.0kDa, 78.0kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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