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Overview
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The protein has a predicted molecular mass of 27.5 kDa after removal of the signal peptide. The apparent molecular mass of B7-H6-His is approximately 35-55 kDa due to glycosylation. B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity.
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- Properties
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Overview