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Recombinant human B7-2 protein with C-terminal human Fc tag

Recombinant human B7-2 protein with C-terminal human Fc tag

Catalog Number:
P001417494ABE
Mfr. No.:
Abe32-17086
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      • Overview

        • The protein has a predicted molecular mass of 51.5 kDa after removal of the signal peptide. This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

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      • Properties
        • Protein Name
          CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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