Recombinant Human Aldehyde Dehydrogenase 1-A2/ALDH1A2 (N-6His)

Recombinant Human Aldehyde Dehydrogenase 1-A2/ALDH1A2 (N-6His)

Catalog Number:
P001412547ABE
Mfr. No.:
Abe32-8772
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      • Overview
        • MW : 58.2kD. Recombinant Human Aldehyde dehydrogenase 1-A2 is produced by our E.coli expression system and the target gene encoding Met1-Ser518 is expressed with a 6His tag at the N-terminus. Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mMNaCl, pH7.5, 20% Glycerol.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          8854

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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