Name: Recombinant Mouse PDGFR a/PDGFRA/CD140a (C-6His)
Price: Inquiry

- Overview
  - MW : 56.9kD. Recombinant Mouse PDGF receptor alpha is produced by our Mammalian expression system and the target gene encoding Leu25-Glu524 is expressed with a 6His tag at the C-terminus. Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-a and - beta. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -aa, - beta beta and -a beta. PDGFRa and PDGFR beta are members of the class III RTK family. Inappropriate PDGFRa and PDGFR beta signaling has been linked to a number of proliferative disorders.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P26618
    
    Gene ID
    
    18595
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Mouse PDGFR a/PDGFRA/CD140a (C-6His)

Recombinant Mouse PDGFR a/PDGFRA/CD140a (C-6His)

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