Name: Recombinant Human ACE-2 (C-Fc) Active
Price: Inquiry

- Overview
  - Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor dont inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95% as determined by reducing SDS-PAGE.
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 20mM Tris-HCl, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4.
    
    Storage
    
    Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles
    
    More Information
    
    UniProt
    
    Q9BYF1
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    Immobilized Human ACE-2-FC at 10μg/ml (100 µl/well) can bind 2019-nCoV S Protein RBD-SD1-mFc. The ED50 of Recombinant 2019-nCoV S Protein RBD-mFc is 15.5 ng/ml .

Recombinant Human ACE-2 (C-Fc) Active

Recombinant Human ACE-2 (C-Fc) Active

More Information

We Also Recommend

Human ACE2 Protein (Fc Tag)

Human ACE2 Protein (FLAG Tag)

Recombinant Rat Dipeptidyl peptidase 4(Dpp4),partial