Name: Recombinant Estrogen Receptor alpha Monoclonal Antibody
Price: 392.00 USD

Overview
- Calculated MW: 119kDa
  Observed MW: 125kDa
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  A synthetic peptide of human Estrogen Receptor alpha
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
  
  Storage
  
  Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
  
  Concentration
  
  300 μg/mL
  
  Antigen
  
  DKFZp686N23123, ER alpha, ER, ER-alpha, Era, ESR, ESR1, ESR1, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Estrogen receptor 1, Estrogen receptor alpha 3*, 4, 5, 6, 7*/822 isoform, Estrogen receptor alpha, Estrogen receptor alpha delta 3*, 4, 5, 6, 7*, 8*/941 isoform, Estrogen receptor alpha delta 3*, 4, 5, 6, 7*/819 2 isoform, Estrogen receptor alpha delta 4 +49 isoform, Estrogen receptor alpha delta 4*, 5, 6, 7*/654 isoform, Estrogen receptor alpha delta 4*, 5, 6, 7, 8*/901 isoform, Estrogen receptor alpha E1 E2 1 2, Estrogen receptor alpha E1 N2 E2 1 2, Estrogen receptor, ESTRR, NR3A1, Nuclear receptor subfamily 3 group A member 1 (Gene ID:2099; UniProt:P03372)
  
  * For reference only.

Applications

Application

WB; IHC-P; IF

Application	Dilutions
WB	1:500-1:1000
IHC	1:50-1:100
IF	1:20-1:100

Recombinant Estrogen Receptor alpha Monoclonal Antibody

Recombinant Estrogen Receptor alpha Monoclonal Antibody

Background

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