Recombinant ILF3 Monoclonal Antibody

Recombinant ILF3 Monoclonal Antibody

Catalog Number:
A001511118RED
Mfr. No.:
RD86948A
Price:
$392
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      • Overview
        • Calculated MW: 131kDa
          Observed MW: 131kDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; rat
          Immunogen
          A synthetic peptide of human ILF3
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          CBTF, Double stranded RNA binding protein 76, Double-stranded RNA-binding protein 76, DRBF, DRBP76, ILF3, ILF3, Interleukin enhancer binding factor 3, Interleukin enhancer-binding factor 3, M phase phosphoprotein 4, M-phase phosphoprotein 4, MPHOSPH4, MPP4, NF AT 90, NF-AT-90, NF110, NF90, NFAR, Nuclear factor associated with dsRNA, Nuclear factor of activated T cells 90 kDa, Nuclear factor of activated T-cells 90 kDa, TCP80, Translational control protein 80 (Gene ID:3609; UniProt:Q12906)

          * For reference only.

      • Applications
        • Application
          WB; IHC-P; IF
        • Application Dilutions
          WB 1:2000-1:5000
          IHC 1:50-1:100
          IF 1:50-1:100

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