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Overview
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The E.coli derived recombinant 22 kDa protein isgenetically engineered peptide which is derived from Dengue Type-2 Envelope. This region also contains a common antigen for Dengue type 2, 3 and 4. Thisprotein is fused to 6xHis tag. Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
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