Name: Ramoplanin
Price: 322.00 USD

- Overview
  - Ramoplanin is a cyclic lipoglycodepsipeptide antimicrobial. It is a complex of structurally related molecules with Ramoplanin A2 as the primary component. Ramoplanin was isolated in the early 1980s as the major metabolite of a strain of Actinoplanes. It is a therapeutic peptide, effective against Gram-positive bacteria including MRSA and MRSE.
    Ramoplanin is soluble in ethanol, methanol, DMF and DMSO.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Ramoplanin binds to the peptidoglycan intermediate Lipid II, blocking its polymerization to form the carbohydrate chains of peptidoglycan, resulting in inhibition of bacterial cell wall biosynthesis.
- Properties
  - CAS Number
    
    76168-82-6
    
    Molecular Formula
    
    C119H154ClN21O40 (for A2)
    
    Molecular Weight
    
    2554.1 (for A2)
    
    Appearance
    
    White solid
    
    Solubility
    
    soluble in ethanol, methanol, DMF and DMSO.
    
    Other Properties
    
    Source: Actinoplanes (strain: ATCC 33076 )
    Purity Level: >95% by HPLC
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Effective against Gram-positive bacteria.
    
    Microbiology Applications: Ramoplanin is effective against antibiotic-resistant Clostridium difficile infection of the gastrointestinal tract. It can be used to study antibiotic-resistant enterococci. Ramoplanin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram positive isolates. Medical microbiologists use AST results to recommend antibiotic treatment options. .