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Rabbit anti-Human Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) IgG fraction polyclonal antibody

Rabbit anti-Human Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) IgG fraction polyclonal antibody

Catalog Number:

A001277510AUS

Mfr. No.:

AUST_PCA-2135a-9

Price:

$760

Size:

1mg

Quantity:

Add to Cart:

- Overview
  - IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (VLIVIFTVLLQSLCVAVTY) corresponding to amino acids 17-35 of human TRAIL. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    polyclonal
    
    Formulation
    
    Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This polyclonal antibody reacts in ELISA and Western blot (1:100 dilution) using the immunizing peptide. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or Apo-2 ligand is a cytokine that belongs to TNF family and induces apoptosis of tumor cells by binding to its receptors, TRAIL R1 (DR4) and TRAIL R2 (DR5). Both Receptors contain death domains and two decoy receptors TRAIL-R3 (DcR1) and TRAIL-R4 (DcR2) that inhibit TRAIL function. TRAIL induces apoptosis and NF?B activation in many tissues and cells.

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