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Overview
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A1 reacts with VP1 of AAV1-12. In immunoprecipitation, an occasional reaction with a non-AAV-derived protein is found.
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Background
A1 reacts with VP1 of adeno-associated virus 1-12 (AAV1-12). In immunoprecipitation, an occasional reaction with a non-AAV-derived protein is found. Epitope mapping experiments (Wobus et al. 2000) identified aa123 to aa131 of VP1 capsid protein as the specific binding region.
Wobus, C. E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281–93 (2000).
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