Name: Rabbit anti-Human Tumor Necrosis Factor-related apoptosis-inducing ligand Receptor 2 (TRAIL R2) IgG fraction polyclonal antibody
Price: 760.00 USD

- Overview
  - IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (LGERLAKQKIEDHLLSSGK) corresponding to amino acids 409-427 of human TRAIL R2. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    polyclonal
    
    Formulation
    
    Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This polyclonal antibody reacts in ELISA and Western blot (1:500 dilution) using the immunizing peptide. Tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL R2 or TRICK 2) or also termed death receptor 5 (DR5) is a type I membrane protein that contains a cytoplasmic death domain. It binds TRAIL and mediates apoptosis via intracellular adaptor molecule FADD/MORT 1 and activation of NF?B.
- Reference
  - Schneider, P. et al. (1997) FEBS Lett. 416, 329-334.
    Walczak, H. et al. (1997) EMBO J. 16, 5386-5397.
    Suliman, A. et al. (2001) Oncogene 20, 2122-213.
    Falschlehner, C. et al. (2007) Int. J. Biochem. Cell Biol. 39, 1462-1475.

Rabbit anti-Human Tumor Necrosis Factor-related apoptosis-inducing ligand Receptor 2 (TRAIL R2) IgG fraction polyclonal antibody

Rabbit anti-Human Tumor Necrosis Factor-related apoptosis-inducing ligand Receptor 2 (TRAIL R2) IgG fraction polyclonal antibody

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