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Rabbit anti-Human p53-associated Parkin-like Cytoplasmic Protein (PARC) IgG fraction polyclonal antibody

Rabbit anti-Human p53-associated Parkin-like Cytoplasmic Protein (PARC) IgG fraction polyclonal antibody

Catalog Number:

A001277512AUS

Mfr. No.:

AUST_PCA-3000a-9

Price:

$760

Size:

1mg

Quantity:

Add to Cart:

- Overview
  - IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (FFFGDEEEDEDEAYD) corresponding to amino acids 2503-2517 of human PARC. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    polyclonal
    
    Formulation
    
    Solution at 0.5 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This polyclonal antibody reacts in ELISA (1: 250 dilution) and Western blot (1: 1,000 dilution) using the immunizing peptide. P53-associated parkin-like cytoplasmic protein (PARC) is a 270 kDa protein that acts as a cytoplasmic anchor for p53 unstressed cells, thereby regulating the localization and subsequent function of p53. It contains a cullin domain and a RING-IBR-RING domain at the carboxy terminus and it is ubiquitously expressed.
- Reference
  - Nikolaev, A.Y. et al. (2003) Cell 112, 29-40.
    Nikolaev, A.Y. & Gu, W. (2003) Cell Cycle 2, 169-171.

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