Rabbit anti-Human Kaiso IgG fraction polyclonal antibody

Rabbit anti-Human Kaiso IgG fraction polyclonal antibody

Catalog Number:
A001277523AUS
Mfr. No.:
AUST_PT-5030a-9
Price:
$760
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (DGSTEFEFIIPESY) corresponding to amino acids 660-673 of human Kaiso. The IgG fraction was purified using Protein G-Sepharose.

          Please contact us at for specific academic pricing.

      • Properties
        • Antibody Type
          polyclonal
          Formulation
          Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
          Storage
          Store at -20°C.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Applications
        • Application Description
          This polyclonal antibody reacts in ELISA (1:50 dilution) using the immunizing peptide. Kaiso is a transcriptional represor that belongs to POZ-zinc finger family of transcription factors implicated in development and cancer. It binds to specific methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and it also binds to non-methylated consensus sequence 5'-CTGCNA-3'. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of represive chromatin structures in taget gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway.
      • Reference
        • Daniel, J.M. & Reynolds, A.B. (1999) Mol. Cell. Biol. 19, 3614-362
          Soubry, A. et al. (2005) Cancer Res. 65, 2224-223
          Kelly, K.F. & Daniel J.M. (2006) Trends Cell. Biol. 16, 578-587. Daniel, J.M. (2007) Biochim. Biophys. Acta 1773, 59-68

    Note: If you don't receive our verification email, do the following:

    Copyright © Amerigo Scientific. All rights reserved.