Name: Rabbit anti-Human Cyclin-dependent Kinase 5 (Cdk5) (epitope b) IgG fraction polyclonal antibody
Price: 760.00 USD

- Overview
  - IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (KCNPVQRISAEEALQH) corresponding to amino acids 268-283 of human Cdk5. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    polyclonal
    
    Formulation
    
    Solution at 1.0 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This polyclonal antibody reacts in ELISA (1: 25 dilution) and Western blot (1: 100 dilution) using the immunizing peptide. Cyclin-dependent kinase 5 (Cdk5) belongs to the Ser/Thr protein kinase family. It is ubiquitously expressed in both cycling and noncycling cells but its activity is detected almost exclusively in brain extracts. Cdk5 is activated by p35 protein which is only expressed in the brain. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
- Reference
  - Pines, J. (1995) Biochem. J. 308, 697-711.
    Maccioni, R. et al. (2001) Eur. J. Biochem. 268, 1518-1527.
    O'Hare, M.J. et al. (2005) J. Neurosci. 25, 8954-8966.
    Angelo, M. et al. (2006) J. Neurochem. 99, 353-370.

Rabbit anti-Human Cyclin-dependent Kinase 5 (Cdk5) (epitope b) IgG fraction polyclonal antibody

Rabbit anti-Human Cyclin-dependent Kinase 5 (Cdk5) (epitope b) IgG fraction polyclonal antibody

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