Name: Rabbit anti-Human c-Myc IgG fraction polyclonal antibody
Price: 760.00 USD

- Overview
  - IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (KHKLEQLRNSCA) corresponding to amino acids 428-439 of human c-Myc. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    polyclonal
    
    Formulation
    
    Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This polyclonal antibody reacts in ELISA and Western blot assays (1: 1,000 dilution) using the immunizing peptide. c-Myc is a transcription factor with apparent molecular weight of 62-67 kDa which plays an important role in the control of cell growth, cell cycle progression, neoplasia, and apoptotic cell death. It contains a basic helix-loop-helix leucine zipper domain required for dimerization and binds DNA as an heterodimer with MAX protein. c-Myc is overexpressed in different tumors such as colorectal, gastric, gallbladder, hepatic, mammary, pulmonary, prostatic, endocrine, as well as hematopoietic neoplasms.
- Reference
  - Eisenman, R.N. (2001) Genes & Dev. 15, 2023-2030.
    Plengaris, S. & Khan, M. (2003) Arch. Biochem. Biophys. 416, 129-136.
    Knoepfler, P.S. (2007) Cancer Res. 67, 5061-606.

Rabbit anti-Human c-Myc IgG fraction polyclonal antibody

Rabbit anti-Human c-Myc IgG fraction polyclonal antibody

We Also Recommend

anti-AAV VP1 mouse monoclonal, A1, lyophilized, purified

anti-AAV VP1/VP2 mouse monoclonal, A69, lyophilized, purified

Anti-AAV VP1/VP2/VP3 mouse monoclonal, B1, AFDyeTM 488 Conjugate