Name: Rabbit anti-Human Beta-Catenin IgG fraction polyclonal antibody
Price: 760.00 USD

- Overview
  - IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (SYLDSGIHSGATTTAPSLSGK) corresponding to amino acids 29-49 of human beta-catenin. The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    polyclonal
    
    Formulation
    
    Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This polyclonal antibody reacts in ELISA and Western blot (1: 2,000 dilution) using the immunizing peptide. The catenins are structurally related cytoplasmic proteins which have been classified as alpha (102-105 kDa), beta (92-97 kDa), and gamma (82-86 Kda). Beta-Catenin plays an important role in the cadherin-mediated anchoring and organization of the cytoskeleton. It is also involved in regulation of gene expression as a mediator of the Wnt signalling pathway. Beta-Catenin associates with the tumor suppressor protein APC and it is implicated in early embryonic development and tumorogenesis.
- Reference
  - Willert, K. & Nusse, R. (1998) Curr. Opin. Genet. Dev. 8 (1), 95-10.
    Kikuchi, A. (2000) Biochem. Biophys. Res. Commun. 268 (2), 243-248.
    Willert, K. & Jones, K.A. (2006) Genes Dev. 20, 1394-1404.

Rabbit anti-Human Beta-Catenin IgG fraction polyclonal antibody

Rabbit anti-Human Beta-Catenin IgG fraction polyclonal antibody

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