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Overview
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Pyrazinecarboxamide, a nicotinamide analogue, is a precursor compound that inhibits Mycobacterium tuberculosis. It is an antitubercular agent. It is used in Mycobacterium detection kits.
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Background
The active moiety of pyrazinamide is Pyrazinoic Acid (POA). POA is thorugh to disrupt membrane energetics and inhbit membrane transport in M. tuberculosis.
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- Properties
- Applications
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Overview